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BiRG publications and funding (in reverse chronological order)
More current publications may be listed on Dr. Doom's or Dr. Raymer's on-line CVs.
To appear soon
J. Gilder, T. Doom, K. Inman, and D. Krane. "Run-specific limits of
detection and quantitation for STR-based DNA testing."
To appear in the Journal of Forensic Sciences, January
2007.
S. Ramachandran, T. Doom, M. Raymer, and D. Krane.
"Parsimony based approach to test the Evolving Master Gene hypothesis
for human ALU repeats."
Accepted for the Proceedings of the
6th IEEE Symposium on Bioinformatics and Bioengineering (BIBE 2006),
August 2006.
E. Heizer, D. Raiford, M. Raymer, T. Doom, R. Miller, and D. Krane.
"Amino acid cost and codon usage biases in six prokaryotic genomes: A
whole genome analysis." Journal of Molecular Biology and Evolution,
accepted and in press.
2006 (partial)
D. Raiford, T. Doom, D. Krane, and M. Raymer. "An
Investigation of Codon Usage Bias Including Visualization and
Quantification in Organisms Exhibiting Multiple Biases". In Proceedings
of the Ohio Collaborative Conference on Bioinformatics (OCCBIO)
2006, Athens (OH), June 2006.
S. Ramachandran, T. Doom, M. Raymer, and D. Krane. "ALU elements as time
series genomic data."
In Proceedings of the Ohio Collaborative Conference on
Bioinformatics (OCCBIO) 2006, Athens (OH), June 2006.
D. Paoletti, T. Doom, M. Raymer, and D. Krane.
"Assesing the implications for close relatives in the event of
similar but non-matching DNA profiles."
Jurimetrics , Vol. 46, No. 2, pp. 161-175, Winter 2006.
2005
P. Anderson, D. Raiford, D. Sweeney, T. Doom, and M. Raymer.
"Stochastic model of protease-ligand reactions." Proceedings of the
5th IEEE Symposium on Bioinformatics and Bioengineering (BIBE 2005),
Minneapolis, Minnesota, pp 306-310, October 2005.
D. Paoletti, T. Doom, C. Krane, M. Raymer, and D. Krane. "Empirical
Analysis of the STR profiles resulting from conceptual mixtures."
Journal of Forensic Sciences, Vol. 50, No. 6, pp. 1361-1366,
November 2005.
M. Peterson, T. Doom, and M. Raymer. "GA-facilitated KNN classifier
optimization with varying similarity measures." Proceedings of the
2005 IEEE Congress on Evolutionary Computation,
vol 3, pp. 2514-2521, 2005.
2004
M. Peterson, T. Doom, and M. Raymer. ``GA-facilitated knowledge
discovery and pattern recognition optimization applied to the
biochemistry of protein solvation.'' Proceedings of ACM
Genetic and Evolutionary Computation Conference (GECCO) 2004,
Seattle (WA), pp. 426-437, June 2004.
M. Raymer, M. Peterson and T. Doom. ``Knowledge discovery in
large biological data sets using hybrid classifier/evolutionary
algorithms", Proceedings the 36th Symposium on the Interface:
Computational Biology and Bioinformatics , Baltimore, MD, May 26 -
29, 2004.
G. Cooper, M. Raymer, T. Doom, D. Krane, and N. Futamura.
``Indexing genomic databases''. Proceedings of 2004 IEEE international
symposium on Bioinformatics and Bioengineering (BIBE) , Taichung
(Taiwan), pp. 587-591, May 2004.
D. Burhans, M. DeJohgh, T. Doom, and M. LeBlanc. ``Bioinformatics
in the undergraduate curriculum: Opportunities for computer science
educators.'' Proceedings of the ACM Special Interest Group on
Computer Science Education (SIGCSE) 2004, Norfolk (VA), March
2004.
T. Doom, M. Raymer, and D. Krane. ``Bioinformatics: Where
Biology meets Computer Science.'' IEEE Potentials,
pgs. 24-28, Vol. 23, No. 1, Feb/March 2004.
J. Gilder, S. Ford, T. Doom, M. Raymer, and D. Krane.
``Systematic differences in electropherogram peak heights reported by
different version of the Genescan (R) software.'' Journal of Forensic
Science, pgs. 92-85, Vol 49, No. 1, January 2004.
2003
M. Raymer, T. Doom, L. Kuhn, and W. Punch. ``Knowledge Discovery
in Medical and Biological Datasets Using a Hybrid Bayes
Classifier/Evolutionary Algorithm.'' IEEE Transactions on
Systems, Man, and Cybernetics, Vol. 33, No. 5, October 2003.
J. Gilder, S. Ford, M. Raymer, T. Doom, D. Krane. ``Differences in
electropherogram peak heights reported by different versions of the
Genescan(R) software.'' 14th International Symposium on Human
Identification (Promega), Phoenix (AZ), September, 2003.
T. Doom, M. Raymer, D. Krane, and O. Garcia. ``Crossing the
interdisciplinary barrier: A baccalaureate computer science option in
bioinformatics.'' IEEE Transactions on Education, Volume
46, No. 3, pp 387-393, August 2003.
D. Sweeney, M. Raymer, and T. Lockwood, ``Antidiabetic and
antimalarial biguanide drugs are metal-interactive antiproteolytic
agents,'' Biochemical Pharmacology, In press.
W. Thompson, S. Ford, T. Doom, M. Raymer, and D. Krane,
``Evaluating forensic DNA evidence: Breaking open the black box (how
to review electronic data).'' The Champion , pgs. 25-28,
Vol. XXVII, No. 3, May 2003.
J. Gilder, D. Krane, T. Doom and M. Raymer,
``Identifing patterns in DNA change.''
Proceedings of the 2003 Midwest Artificial Intelligence and
Cognitive Science Conference, Vol. 34, pgs. 78-84.
Columbus OH, April 2003.
MS-Word Download.
Powerpoint Download.
J. Gilder, S. Ford, T. Doom, M. Raymer, and D. Krane,
``Differences in electropherogram peak heights reported by
different version of the Genescan software.'' Journal
of Forensic Science, submitted for review.
W. Thompson, S. Ford, T. Doom, M. Raymer, and D. Krane,
``Evaluating forensic DNA evidence: Essential elements of a
competent defense review.'' The Champion,
pgs. 16-25 (Cover Story), Vol. XXVII, No. 3, April 2003.
D. Millhorn, R. Fyffe, O. Garcia, M. Raymer, T. Doom, D. Krane, et al.,
``A genome research institute in Ohio,'' Ohio BRTT Grant, $1,700,000,
Period January 2003 - 2005.
2002
M. Peterson, T. Doom, and M. Raymer,
``GA-facilitated cosine classifer optimization with application to the
biochemistry of protien-water interactions.''
Bioinformatics Workshop, 6th International Conference/Exhibition
on High Performance Computing (HPC-Asia 2002) ,
Banglore (India), December, 2002.
D. Krane, T. Doom, M. Raymer, and O. Garcia,
``An interdisciplinary undergraduate bioinformatics curriculum for
biological scientists.'' Journal of College teaching
, submitted for review.
T. Doom, M. Raymer, D. Krane, and O. Garcia,
``Crossing the interdisciplinary barrier: A baccalaureate computer
science option in bioinformatics.''
IEEE Transactions on Education , in press Vol. 46, Num. 3.
PDF Download
Raymer, M., T. Doom, L. Kuhn, and W. Punch, ``Knowledge Discovery
in Medical and Biological Datasets Using a Hybrid Bayes
Classifier/Evolutionary Algorithm.'' IEEE Transactions on
System, Man, and Cybernetics , accepted.
T. Doom, M. Raymer, D. Krane, and O. Garcia,
``A proposed undergraduate bioinformatics curriculum for computer scientists.''
Proceedings of the 2002 ACM Special Interest Group on
Computer Science Education (SIGCSE 2002),
Convington (KY), February, 2002, 34:78-84.
PDF Download
2001
J. Gilder, M. Raymer, T. Doom,
``PocketMol: A Molecular Visualization Program for the Pocket PC.''
poster at the Symposium on Bioinformatics for Drug-Development,
Toledo (OH), November, 2001.
Powerpoint Download
M. Peterson, M. Raymer, T. Doom,
``Prediction Enhancement of Protein-Water Binding Conservation through
Evolutionary Computation.''
poster at the Symposium on Bioinformatics for Drug-Development,
Toledo (OH), November, 2001.
Powerpoint Download
D. Sweeney, T. Doom, M. Raymer,
``Profile Combinatorics for Fragment Selection in Comparative Protein
Structure Modeling.''
poster at the Symposium on Bioinformatics for Drug-Development,
Toledo (OH), November, 2001.
J. Gilder, M. Raymer, T. Doom,
``PocketMol: A Molecular Visualization Tool for the PocketPC.''
2001 IEEE International Symposium on Bioinformatics and Bioengineering (BIBE
2001), November, 2001.
PDF Download
D. Sweeney, J. Alter, M. Raymer, T. Doom,
``Profile Combinatorics for Fragment Selection in Comparative Modeling.''
2001 IEEE International Symposium on Bioinformatics and Bioengineering (BIBE
2001), November, 2001.
Postscript Download
T. Doom and O. Garcia,
``Bioinformatics: An option in computer science.''
Proceedings of the 2001 Midwest Artificial Intelligence and
Cognitive Science Conference, March, 2001.
M. Raymer, T. Doom, and D. Krane (co-P.I.s),
``Crossing the interdisciplinary barrier: An integrated
undergraduate program in bioinformatics,''
NSF CISE Educational Innovation Grant #EIA-0122582, $840,300,
Period: September 2001 - August 2004.
D. Krane, M. Raymer, T. Doom, and O. Garcia (co-P.I.s),
``Commercialization of forensic DNA typing expertise,''
Wright State University Technology Commercialization Grant
#664723, $99,951, Period: September 2001 - August 2002.
T. Doom, J. Gallager, M. Raymer (co-P.I.s),
``Cluster Computing for Bioinformatics and Biocontrol,''
Ohio Shared Computing Center Resourses Grant.
T. Doom (P.I.),
``Development of a bioinformatics option in computer science and engineering,''
Research Initiation Grant, Wright State University,
#241656, $8,000, Period: 15 April 2001 - 31 May 2002.
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